Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Chloroquine | inhibits arginase in a dose-dependent manner, and displays a linear competitive inhibition on sickle erythrocyte arginase | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.81 | - |
L-arginine | at pH 6.8 and 37°C | Homo sapiens | |
2.08 | - |
L-arginine | at pH 6.8 and 37°C | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | Homo sapiens | - |
L-ornithine + urea | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | sickle erythrocyte | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine + H2O | - |
Homo sapiens | L-ornithine + urea | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-arginine amidinohydrolase | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.023 | - |
Chloroquine | at pH 6.8 and 37°C | Homo sapiens | |
0.041 | - |
Chloroquine | at pH 7.4 and 37°C | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.077 | - |
at pH 6.8 and 37°C | Homo sapiens | Chloroquine | |
0.109 | - |
at pH 7.4 and 37°C | Homo sapiens | Chloroquine |