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Literature summary for 3.5.1.118 extracted from

  • Seebeck, F.P.
    In vitro reconstitution of Mycobacterial ergothioneine biosynthesis (2010), J. Am. Chem. Soc., 132, 6632-6633.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24139
-
x * 24139, calculated from sequence Mycolicibacterium smegmatis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O Mycolicibacterium smegmatis the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
-
?
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O Mycolicibacterium smegmatis ATCC 700084 the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
-
?

Organism

Organism UniProt Comment Textmining
Mycolicibacterium smegmatis A0R5M9
-
-
Mycolicibacterium smegmatis ATCC 700084 A0R5M9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O
-
Mycolicibacterium smegmatis S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
-
?
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria Mycolicibacterium smegmatis S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
-
?
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O
-
Mycolicibacterium smegmatis ATCC 700084 S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
-
?
S-(hercyn-2-yl)-gamma-L-glutamyl-L-cysteine S-oxide + H2O the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria Mycolicibacterium smegmatis ATCC 700084 S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate
-
?

Subunits

Subunits Comment Organism
? x * 24139, calculated from sequence Mycolicibacterium smegmatis

Synonyms

Synonyms Comment Organism
EgtC
-
Mycolicibacterium smegmatis

General Information

General Information Comment Organism
metabolism the enzyme is part of the biosynthesis pathway of ergothioneine in mycobacteria Mycolicibacterium smegmatis