Any feedback?
Literature summary for 3.5.1.11 extracted from
- Study of different media for production of penicillin G acylase from Bacillus megaterium ATCC 14945 (2000), Appl. Biochem. Biotechnol., 84-86, 655-663.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | production of 6-aminopenicillanate as precursor for the production of semi-synthetic beta-lactam derivatives | Priestia megaterium |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Priestia megaterium | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| penicillin G + H2O | Priestia megaterium | enzyme specific for penicillin G | 6-aminopenicillanic acid + phenylacetic acid | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Priestia megaterium | - |
strain ATCC 14945, enzyme production is repressed when glucose is added to the culture medium, best enzyme production when cultured on casein (hydrolyzed using Alcalase) and fresh cheese whey | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| penicillin G + H2O | enzyme specific for penicillin G | Priestia megaterium | 6-aminopenicillanic acid + phenylacetic acid | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| penicillin G acylase | - |
Priestia megaterium |
| PGA | - |
Priestia megaterium |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
