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Literature summary for 3.4.24.87 extracted from

  • McKinnon, T.A.; Chion, A.C.; Millington, A.J.; Lane, D.A.; Laffan, M.A.
    N-linked glycosylation of VWF modulates its interaction with ADAMTS13 (2008), Blood, 111, 3042-3049.
    View publication on PubMed
Search for more literature for 3.4.24.87

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
von Willebrand factor + H2O Homo sapiens ADAMTS13 cleaves the bond Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Collagen + H2O
-
 Homo sapiens ?
-
 ?
additional information PNGase-treated von Willebrand factor is more succeptible to proteolysis by ADAMTS13 and binds with increased affinity Homo sapiens ?
-
 ?
von Willebrand factor + H2O ADAMTS13 cleaves the bond Tyr842-Met843 within the A2 domain, i.e. Tyr1605-Met1606 in von Willebrand factor UniProt Id P04275 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
ADAMTS13
-
 Homo sapiens
von Willebrand factor cleaving protease
-
 Homo sapiens
VWF cleaving protease
-
 Homo sapiens