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Literature summary for 3.4.24.81 extracted from

  • Kuhn, P.H.; Colombo, A.V.; Schusser, B.; Dreymueller, D.; Wetzel, S.; Schepers, U.; Herber, J.; Ludwig, A.; Kremmer, E.; Montag, D.; Mueller, U.; Schweizer, M.; Saftig, P.; Braese, S.; Lichtenthaler, S.F.
    Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function (2016), eLife, 5, e12748 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-amyloid precursor protein + H2O Mus musculus
-
sAPP-alpha fragment + C-terminal fragment
-
?
cadherin-6 + H2O Mus musculus
-
?
-
?
CHL1 + H2O Mus musculus
-
?
-
?
CNTN2 + H2O Mus musculus
-
?
-
?
E-cadherin + H2O Mus musculus
-
?
-
?
fractalkine CX3CL1 + H2O Mus musculus
-
?
-
?
ISLR2 + H2O Mus musculus
-
?
-
?
leucine-rich repeat-containing protein 4B + H2O Mus musculus
-
?
-
?
matrix metalloproteinase-17 + H2O Mus musculus
-
?
-
?
neurexin 3 + H2O Mus musculus
-
?
-
?
neuroligin-1 + H2O Mus musculus
-
?
-
?
Notch + H2O Mus musculus
-
?
-
?
NRCAM + H2O Mus musculus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus O35598
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-amyloid precursor protein + H2O
-
Mus musculus sAPP-alpha fragment + C-terminal fragment
-
?
cadherin-6 + H2O
-
Mus musculus ?
-
?
CHL1 + H2O
-
Mus musculus ?
-
?
CNTN2 + H2O
-
Mus musculus ?
-
?
E-cadherin + H2O
-
Mus musculus ?
-
?
fractalkine CX3CL1 + H2O
-
Mus musculus ?
-
?
ISLR2 + H2O
-
Mus musculus ?
-
?
leucine-rich repeat-containing protein 4B + H2O
-
Mus musculus ?
-
?
matrix metalloproteinase-17 + H2O
-
Mus musculus ?
-
?
neurexin 3 + H2O
-
Mus musculus ?
-
?
neuroligin-1 + H2O
-
Mus musculus ?
-
?
Notch + H2O
-
Mus musculus ?
-
?
NRCAM + H2O
-
Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
a-disintegrin-and-metalloprotease 10
-
Mus musculus
ADAM10
-
Mus musculus