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Literature summary for 3.4.24.73 extracted from

  • Pinto, A.F.; Terra, R.M.; Guimaraes, J.A.; Fox, J.W.
    Mapping von Willebrand factor A domain binding sites on a snake venom metalloproteinase cysteine-rich domain (2007), Arch. Biochem. Biophys., 457, 41-46.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
additional information quantitative binding analysis of synthetic peptides designed based on the sequence of the cysteine-rich domain of jararhagin to the substrate Von Willebrand factor, overview Bothrops jararaca

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Bothrops jararaca
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bothrops jararaca the enzyme is a P-III snake venom metalloproteinase and a potent hemorrhagin ?
-
?
von Willebrand factor + H2O Bothrops jararaca
-
?
-
?

Organism

Organism UniProt Comment Textmining
Bothrops jararaca
-
-
-

Purification (Commentary)

Purification (Comment) Organism
synthetic peptides designed based on the sequence of the cysteine-rich domain of jararhagin are purified to homogeneity by gel filtration Bothrops jararaca

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Bothrops jararaca
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is a P-III snake venom metalloproteinase and a potent hemorrhagin Bothrops jararaca ?
-
?
von Willebrand factor + H2O
-
Bothrops jararaca ?
-
?
von Willebrand factor + H2O mapping of Von Willebrand factor A domain binding sites on the enzyme's cysteine-rich domain, binding between jararhagin cysteine-rich domain and Von Willebrand factor A1 domain, protein-protein interactions, molecular modeling, overview Bothrops jararaca ?
-
?