Literature summary for 3.4.24.65 extracted from

Fan, J.; Wang, X.; Wu, L.; Matsumoto, S.I.; Liang, J.; Koike, T.; Ichikawa, T.; Sun, H.; Shikama, H.; Sasaguri, Y.; Watanabe, T.
Macrophage-specific overexpression of human matrix metalloproteinase-12 in transgenic rabbits (2004), Transgenic Res., 13, 261-269.

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Cloned(Commentary)

Cloned (Comment)	Organism
generation of transgenic rabbits that express human (h)MMP-12 gene under the control of a macrophage-specific promoter, the human scavenger receptor promoter. This transgenic rabbit model with increased expression of hMMP-12 may become a useful model for further mechanistic studies of MMP-12 in in inflammatory diseases and cancer invasion, it is also an ideal model for testing the in vivo action of MMP-12 inhibitors	Homo sapiens

Cloned (Comment)

Organism

generation of transgenic rabbits that express human (h)MMP-12 gene under the control of a macrophage-specific promoter, the human scavenger receptor promoter. This transgenic rabbit model with increased expression of hMMP-12 may become a useful model for further mechanistic studies of MMP-12 in in inflammatory diseases and cancer invasion, it is also an ideal model for testing the in vivo action of MMP-12 inhibitors

Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	recombinant	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
beta-casein + H2O	-	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
hMMP-12	-	Homo sapiens
Matrix metalloproteinase-12	-	Homo sapiens

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Release 2023.1 (January 2023)