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Literature summary for 3.4.23.38 extracted from

  • Rasina, D.; Otikovs, M.; Leitans, J.; Recacha, R.; Borysov, O.V.; Kanepe-Lapsa, I.; Domraceva, I.; Pantelejevs, T.; Tars, K.; Blackman, M.J.; Jaudzems, K.; Jirgensons, A.
    Fragment-based discovery of 2-aminoquinazolin-4(3H)-ones as novel class nonpeptidomimetic inhibitors of the plasmepsins I, II, and IV (2016), J. Med. Chem., 59, 374-387 .
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
LV-928
-
 Plasmodium falciparum
pepstatin A
-
 Plasmodium falciparum
TCMDC-134674
-
 Plasmodium falciparum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Hemoglobin + H2O Plasmodium falciparum
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Plasmodium falciparum P39898 isolate 3D7
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Hemoglobin + H2O
-
 Plasmodium falciparum ?
-
 ?

Synonyms

Synonyms Comment Organism
PLm I
-
 Plasmodium falciparum