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Literature summary for 3.4.23.16 extracted from

  • Olajuyigbe, F.M.; Demitri, N.; De Zorzi, R.; Geremia, S.
    Developing HIV-1 protease inhibitors through stereospecific reactions in protein crystals (2016), Molecules, 21, 1458 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.23.16

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21-Gold (DE3)pLysS cells Human immunodeficiency virus 1

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method, using 0.25 M sodium citrate pH 6.0, 10% (v/v) DMSO, and 40%-60% (w/v) saturated ammonium sulfate Human immunodeficiency virus 1

Inhibitors

Inhibitors Comment Organism Structure
4,5-anhydro-1,2,6-trideoxy-2-[[N-(phenoxyacetyl)-L-valyl]amino]-1,6-diphenyl-D-galactitol
-
 Human immunodeficiency virus 1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Gag polyprotein + H2O Human immunodeficiency virus 1
-
 ?
-
 ?
Gag-Pol polyprotein + H2O Human immunodeficiency virus 1
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Human immunodeficiency virus 1 Q7SSI0
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Human immunodeficiency virus 1

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gag polyprotein + H2O
-
 Human immunodeficiency virus 1 ?
-
 ?
Gag-Pol polyprotein + H2O
-
 Human immunodeficiency virus 1 ?
-
 ?

Synonyms

Synonyms Comment Organism
HIV-1 protease
-
 Human immunodeficiency virus 1