Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-chloropyridin-3-yl 1-naphthoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 2-nitrobenzoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 2-oxo-2H-chromene-3-carboxylate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 3-nitrobenzoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 4-chlorobenzoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 5-(2-nitrophenyl)-2-furoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 5-(3-nitrophenyl)-2-furoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 5-(4-chloro-2-nitrophenyl)-2-furoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 5-(4-chlorophenyl)-2-furoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl 5-(4-nitrophenyl)-2-furoate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl isonicotinate | - |
Severe acute respiratory syndrome-related coronavirus | |
5-chloropyridin-3-yl nicotinate | - |
Severe acute respiratory syndrome-related coronavirus | |
additional information | molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro | Severe acute respiratory syndrome-related coronavirus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Severe acute respiratory syndrome-related coronavirus | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00006 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 5-(4-nitrophenyl)-2-furoate | |
0.000063 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 5-(4-chlorophenyl)-2-furoate | |
0.000108 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 2-oxo-2H-chromene-3-carboxylate | |
0.000122 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 5-(4-chloro-2-nitrophenyl)-2-furoate | |
0.000124 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 1-naphthoate | |
0.000164 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl isonicotinate | |
0.000208 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 5-(2-nitrophenyl)-2-furoate | |
0.000333 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 2-nitrobenzoate | |
0.000434 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 4-chlorobenzoate | |
0.0005 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 5-(3-nitrophenyl)-2-furoate | |
0.000648 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl 3-nitrobenzoate | |
0.000697 | - |
- |
Severe acute respiratory syndrome-related coronavirus | 5-chloropyridin-3-yl nicotinate |