Cloned (Comment) | Organism |
---|---|
caspase-9S is cloned from human liver cDNA | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
nitrosylation | nitrosylation of caspase-9 at C163 is dependent, at least in part, on subcellular localization. 68% of the procaspase-9 in mitochondria is nitrosylated and 11% of the procaspase-9 in the cytoplasm in unstimulated 10C9 human B cells | Homo sapiens |
phosphoprotein | the kinases PKB-Akt and ERK2 are involved in the phosphorylation of human caspase-9 at Ser196 and Thr125, respectively | Homo sapiens |
proteolytic modification | proteolytic processing is associated with the removal of a leader sequence, processing by caspase-3 at amino acid 130 and 330. Autolytic processing at amino acid 307 and 315 | Homo sapiens |
proteolytic modification | proteolytic processing is associiated with the removal of a leader sequence, processing by caspase-3 at amino acid 130 and 330. Autolytic processing at amino acid 307 and 315 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-cell | 10C9 | Homo sapiens | - |
B-lymphocyte | 10C9 | Homo sapiens | - |
liver | - |
Homo sapiens | - |