Literature summary for 3.4.22.60 extracted from

Agniswamy, J.; Fang, B.; Weber, I.T.
Conformational similarity in the activation of caspase-3 and -7 revealed by the unliganded and inhibited structures of caspase-7 (2009), Apoptosis, 14, 1135-1144.

Search for more literature for 3.4.22.60

Cloned(Commentary)

Cloned (Comment)	Organism
His-tagged version expressed in Escherichia coli	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
hanging drop vapor diffusion method	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
N-acetyl-Trp-Glu-His-Asp-CHO	-	Homo sapiens
N-acetyl-Tyr-Val-Ala-Asp-CHO	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
immobilized metal ion affinity chromatography (Ni2+), gel filtration	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-acetyl-Asp-Glu-Val-Asp-p-nitroanilide + H2O	-	Homo sapiens	N-acetyl-Asp-Glu-Val-Asp + p-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
caspase-7	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0044	-	N-acetyl-Trp-Glu-His-Asp-CHO	-	Homo sapiens
0.0124	-	N-acetyl-Tyr-Val-Ala-Asp-CHO	-	Homo sapiens

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Release 2023.1 (January 2023)