Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpeptin | complete inhibition at 0.5 mM | Cavia porcellus | |
N-acetyl-Leu-Leu-Nle-CHO | complete inhibition at 0.5 mM | Cavia porcellus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | calpain-1 is relocated and translocated from cytoplasm to plasma membrane during capacitation | Cavia porcellus | 5737 | - |
plasma membrane | calpain-1 is relocated and translocated from cytoplasm to plasma membrane during capacitation | Cavia porcellus | 5886 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | dependent on | Cavia porcellus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
x * 80000, SDS-PAGE | Cavia porcellus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
filamin-1 + H2O | Cavia porcellus | - |
? | - |
? | |
spectrin + H2O | Cavia porcellus | - |
? | - |
? | |
utrophin + H2O | Cavia porcellus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
sperm | - |
Cavia porcellus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
filamin-1 + H2O | - |
Cavia porcellus | ? | - |
? | |
spectrin + H2O | - |
Cavia porcellus | ? | - |
? | |
utrophin + H2O | - |
Cavia porcellus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 80000, SDS-PAGE | Cavia porcellus |
General Information | Comment | Organism |
---|---|---|
physiological function | calpain-1 inhibits the acrosome reaction and alters the plasma membrane-associated cytoskeleton in spermatozoa | Cavia porcellus |