Inhibitors | Comment | Organism | Structure |
---|---|---|---|
kushennol F | shows inhibitory effects on the bone resorption process related to cathepsin K | Homo sapiens | |
Phe-Phe-fluoromethylketone | - |
Homo sapiens | |
sophoraflavanone G | shows inhibitory effects on the bone resorption process related to cathepsin K | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P43235 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
osteoclast | - |
Homo sapiens | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000047 | - |
pH and temperature not specified in the publication | Homo sapiens | Phe-Phe-fluoromethylketone | |
0.00879 | - |
pH and temperature not specified in the publication | Homo sapiens | kushennol F | |
0.0272 | - |
pH and temperature not specified in the publication | Homo sapiens | sophoraflavanone G |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme accounts for the increase in bone resorption in metabolic bone disorders such as postmenopausal osteoporosis | Homo sapiens |