Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Collagen type I | fibronectin and type I collagen addition inhibited the disruptive activity of the enzyme in human fibroblasts | Porphyromonas gingivalis | |
fibronectin | fibronectin and type I collagen addition inhibited the disruptive activity of the enzyme in human fibroblasts | Porphyromonas gingivalis | |
leupeptin | - |
Porphyromonas gingivalis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Porphyromonas gingivalis | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
integrin subunit alpha2 + H2O | Porphyromonas gingivalis | - |
? | - |
? | |
integrin subunit alpha2 + H2O | Porphyromonas gingivalis ATCC 33277 | - |
? | - |
? | |
integrin subunit beta1 + H2O | Porphyromonas gingivalis | - |
? | - |
? | |
integrin subunit beta1 + H2O | Porphyromonas gingivalis ATCC 33277 | - |
? | - |
? | |
integrin subunit beta3 + H2O | Porphyromonas gingivalis | - |
? | - |
? | |
integrin subunit beta3 + H2O | Porphyromonas gingivalis ATCC 33277 | - |
? | - |
? | |
additional information | Porphyromonas gingivalis | enzyme disrupts interaction between fibronectin and integrin in human fibroblasts, leading to cell death of detached fibroblasts, which contributes to the tissue damage in periodontal disease caused by Porphyromonas gingivalis | ? | - |
? | |
additional information | Porphyromonas gingivalis ATCC 33277 | enzyme disrupts interaction between fibronectin and integrin in human fibroblasts, leading to cell death of detached fibroblasts, which contributes to the tissue damage in periodontal disease caused by Porphyromonas gingivalis | ? | - |
? | |
profibronectin + H2O | Porphyromonas gingivalis | - |
fibronectin + ? | - |
? | |
profibronectin + H2O | Porphyromonas gingivalis ATCC 33277 | - |
fibronectin + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | - |
strain ATCC33277 | - |
Porphyromonas gingivalis ATCC 33277 | - |
strain ATCC33277 | - |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
integrin subunit alpha2 + H2O | - |
Porphyromonas gingivalis | ? | - |
? | |
integrin subunit alpha2 + H2O | - |
Porphyromonas gingivalis ATCC 33277 | ? | - |
? | |
integrin subunit beta1 + H2O | - |
Porphyromonas gingivalis | ? | - |
? | |
integrin subunit beta1 + H2O | - |
Porphyromonas gingivalis ATCC 33277 | ? | - |
? | |
integrin subunit beta3 + H2O | - |
Porphyromonas gingivalis | ? | - |
? | |
integrin subunit beta3 + H2O | - |
Porphyromonas gingivalis ATCC 33277 | ? | - |
? | |
additional information | enzyme disrupts interaction between fibronectin and integrin in human fibroblasts, leading to cell death of detached fibroblasts, which contributes to the tissue damage in periodontal disease caused by Porphyromonas gingivalis | Porphyromonas gingivalis | ? | - |
? | |
additional information | enzyme disrupts interaction between fibronectin and integrin in human fibroblasts, leading to cell death of detached fibroblasts, which contributes to the tissue damage in periodontal disease caused by Porphyromonas gingivalis | Porphyromonas gingivalis ATCC 33277 | ? | - |
? | |
profibronectin + H2O | - |
Porphyromonas gingivalis | fibronectin + ? | - |
? | |
profibronectin + H2O | - |
Porphyromonas gingivalis ATCC 33277 | fibronectin + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Arg-gingipain | - |
Porphyromonas gingivalis |
Arginine-specific cysteine protease | - |
Porphyromonas gingivalis |
RGP | - |
Porphyromonas gingivalis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Porphyromonas gingivalis |