Crystallization (Comment) | Organism |
---|---|
mutant Y63A displays promoted self-activated proteolysis, which is a result of an enlarged entrance pore | Staphylococcus aureus |
Protein Variants | Comment | Organism |
---|---|---|
Y63A | gain-of-function mutant, inhibits staphylococcal growth. The mutant becomes an uncontrolled protease that actively hydrolyzes cell division protein FtsZ in vitro. Expression of mutant phenocopies treatment with acyldepsipeptides, inhibition of cell division occurs as does showing sterilizing with rifampicin antibiotics | Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | P63786 | - |
- |
Staphylococcus aureus MW2 | P63786 | - |
- |