Application | Comment | Organism |
---|---|---|
medicine | enzyme is a target for discovery, design of direct inhibitors and development of antithrombotic agents, overview | Homo sapiens |
pharmacology | enzyme is a target for discovery, design of direct inhibitors and development of antithrombotic agents, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
prothrombin + H2O | Homo sapiens | enzyme is involved in thrombotic complications of artherosclerosis and following diseases, overview | thrombin + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
selective cleavage of Arg-/-Thr and then Arg-/-Ile bonds in prothrombin to form thrombin | scutelarin has similar specificity | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
prothrombin + H2O | - |
Homo sapiens | thrombin + ? | - |
? | |
prothrombin + H2O | enzyme is involved in thrombotic complications of artherosclerosis and following diseases, overview | Homo sapiens | thrombin + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
factor Xa | - |
Homo sapiens |
More | the enzyme belongs to the peptidase family S1, i.e. trypsin family | Homo sapiens |