Literature summary for 3.4.21.59 extracted from

Yeong, P.; Ning, Y.; Xu, Y.; Li, X.; Yin, L.
Tryptase promotes human monocyte-derived macrophage foam cell formation by suppressing LXRalpha activation (2010), Biochim. Biophys. Acta, 1801, 567-576.

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Inhibitors

Inhibitors	Comment	Organism	Structure
APC366	N-(1-hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide, selective inhibitor of mast cell tryptase	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lung	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
Mast cell tryptase	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	tryptase increases the lipid accumulation in human monocyte THP-1-derived macrophages and promotes foam cell formation in vitro via suppressing LXRalpha activation	Homo sapiens

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Release 2023.1 (January 2023)