Literature summary for 3.4.21.59 extracted from

Alter, S.C.; Schwartz, L.B.
Effect of histamine and divalent cations on the activity and stability of tryptase from human mast cells (1989), Biochim. Biophys. Acta, 991, 426-430.

Search for more literature for 3.4.21.59

General Stability

General Stability	Organism
calcium destabilizes	Homo sapiens
heparin stabilizes	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
Calcium	5 mM is needed to cause an irreversible 50% loss of activity after 60 min at room temperature	Homo sapiens
histamine	-	Homo sapiens
additional information	not affected by the protein inhibitors of serine proteinases normally present in human extracellular fluids	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
mast cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Tosyl-Gly-Pro-Lys 4-nitroanilide + H2O	-	Homo sapiens	Tosyl-Gly-Pro-Lys + 4-nitroaniline	-	?

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Release 2023.1 (January 2023)