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BRENDA support

Literature summary for 3.4.21.5 extracted from

  • Arumugam, J.; Bukkapatnam, S.T.; Narayanan, K.R.; Srinivasa, A.R.
    Random forests are able to identify differences in clotting dynamics from kinetic models of thrombin generation (2016), PLoS ONE, 11, e0153776 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
diagnostics concentrations of active alpha-thrombin, tissue factor-factor VIIa-factor Xa ternary complex, and intrinsic tenase complex with factor X, at specific time windows, can be used to classify acute coronary syndromes to an accuracy of about 87.2%. Such a combination can be used to efficiently assay the coagulation system Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P00734 prothrombin
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