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Literature summary for 3.4.21.4 extracted from

  • Legowska, A.; Debowski, D.; Lesner, A.; Wysocka, M.; Rolka, K.
    Introduction of non-natural amino acid residues into the substrate-specific P(1) position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors (2009), Bioorg. Med. Chem., 17, 3302-3307.
    View publication on PubMed
Search for more literature for 3.4.21.4

Inhibitors

Inhibitors Comment Organism Structure
Bovine pancreatic trypsin inhibitor
-
 Bos taurus
Gly-L-Arg-L-Cys-L-Thr-L-Lys-L-Ser-L-Ile-L-Pro-L-Pro-L-Ile-L-Cys-L-Phe-L-Pro-L-Asp sun flower trypsin inhibitor SFTI-1 Bos taurus
additional information trypsin is not inhibited by N-(4-aminobutyl)-L-Arg-L-Cys-L-Thr-L-Lys-L-Ser-L-Ile-L-Pro-L-Pro-L-Ile-L-Cys-L-Phe-L-Pro-L-Asp and N-benzylglycine-L-Arg-L-Cys-L-Thr-L-Lys-L-Ser-L-Ile-L-Pro-L-Pro-L-Ile-L-Cys-L-Phe-L-Pro-L-Asp Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-L-Phe-L-Ala-L-Thr-(4-guanidino)-L-Phe-NH-(3-carbamoyl-4-nitrophenol) + H2O
-
 Bos taurus acetyl-L-Phe-L-Ala-L-Thr-(4-guanidino)-L-Phe + 5-amino-2-nitrobenzamide
-
 ?
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-7-amido-4-methylcoumarin + H2O
-
 Bos taurus succinyl-L-Ala-L-Ala-L-Pro-L-Lys + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
beta-trypsin
-
 Bos taurus