Cloned (Comment) | Organism |
---|---|
expression of an N-terminally truncated factor VII in Escherichia coli | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
N-terminally truncated factor VII, activated recombinant factor VII is crystallized in the presence of the reversible S1-site inhibitor benzamidine | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzamidine | - |
Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | bound to the backbone-carbonyl groups of Asp72 and Glu75, and to the side-chain carboxylate groups of Glu70 and Glu80 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P08709 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant factor VII | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-methylsulfonyl-D-Phe-Gly-Arg-4-nitroanilide + H2O | - |
Homo sapiens | N-methylsulfonyl-D-Phe-Gly-Arg + 4-nitroaniline | - |
? |