Literature summary for 3.4.21.117 extracted from

Vasilopoulos, Y.; Cork, M.J.; Murphy, R.; Williams, H.C.; Robinson, D.A.; Duff, G.W.; Ward, S.J.; Tazi-Ahnini, R.
Genetic association between an AACC insertion in the 3UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis (2004), J. Invest. Dermatol., 123, 62-66.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	AACC insertion in the stratum corneum chymotryptic enzyme gene may result in a change to activity of stratum corneum chymotryptic enzyme within the skin barrier. Stratum corneum chymotryptic enzyme could have an important role in the development of atopic dermatitis	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P49862	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	AACC insertion in the stratum corneum chymotryptic enzyme gene may result in a change to activity of stratum corneum chymotryptic enzyme within the skin barrier. Stratum corneum chymotryptic enzyme could have an important role in the development of atopic dermatitis	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
SCCE	-	Homo sapiens

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Release 2023.1 (January 2023)