Literature summary for 3.4.17.22 extracted from

Thomas, L.N.; Chedrawe, E.R.; Barnes, P.J.; Too, C.K.L.
Prolactin/androgen-inducible carboxypeptidase-D increases with nitrotyrosine and Ki67 for breast cancer progression in vivo, and upregulates progression markers VEGF-C and Runx2 in vitro (2017), Breast Cancer Res. Treat., 164, 27-40 .

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Application

Application	Comment	Organism
medicine	The CPD-Arg-nitric oxide pathway contributes to breast cancer progression in vitro and in vivo. There are progressive increases in CPD, nitrotyrosine, Ki67, and Cullin-3 from low levels in benign tissues to high levels in ductal carcinoma in situ, low-grade, high-grade, and triple-negative breast cancer. CPD and nitrotyrosine staining are closely associated, implicating CPD in nitric oxide production	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O75976	-	-

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Release 2023.1 (January 2023)