Literature summary for 3.4.15.1 extracted from

Oh, H.; Kang, D.G.; Lee, S.; Lee, Y.; Lee, H.S.
Angiotensin converting enzyme (ACE) inhibitory alkaloids from Fritillaria ussuriensis (2003), Planta Med., 69, 564-565.

Search for more literature for 3.4.15.1

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	the presence of verticione, verticine, peimisine may be responsible, at least in part, for the antihypertensive action of the bulbs of Fritillaria ussuriensis	Rattus norvegicus
peimisine	IC50: 0.5265 mM	Rattus norvegicus
verticine	IC50: 0.3128 mM	Rattus norvegicus
verticinone	IC50: 0.165 mM	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood plasma	-	Rattus norvegicus	-

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.165	-	IC50: 0.165 mM	Rattus norvegicus	verticinone
0.3128	-	IC50: 0.3128 mM	Rattus norvegicus	verticine
0.5265	-	IC50: 0.5265 mM	Rattus norvegicus	peimisine

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Release 2023.1 (January 2023)