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Literature summary for 3.4.14.5 extracted from

  • Ansorge, S.; Bank, U.; Heimburg, A.; Helmuth, M.; Koch, G.; Tadje, J.; Lendeckel, U.; Wolke, C.; Neubert, K.; Faust, J.; Fuchs, P.; Reinhold, D.; Thielitz, A.; Taeger, M.
    Recent insights into the role of dipeptidyl aminopeptidase IV (DPIV) and aminopeptidase N (APN) families in immune functions (2009), Clin. Chem. Lab. Med., 47, 253-261.
    View publication on PubMed
Search for more literature for 3.4.14.5

Inhibitors

Inhibitors Comment Organism Structure
Lys[Z(NO2)]-pyrrolidide non-specific DPIV inhibitor Mus musculus
Lys[Z(NO2)]-thiazolidide non-specific DPIV inhibitor Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
artery in artery DPIV represents 92% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
blood plasma in blood plasma DPIV represents 78% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
brain in brain DPIV represents 22% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
colon in colon DPIV represents 33% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
duodenum in duodenum DPIV represents 89% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
heart in heart DPIV represents 71% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
ileum in ileum DPIV represents 94% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
kidney in kidney DPIV represents 92% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
liver in liver DPIV represents 94% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
lung in lung DPIV represents 94% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
lymph node in lymph nodes DPIV represents 62% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
pancreas in pancreas DPIV represents 14% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
skin in skin DPIV represents 79% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
splenocyte in spleen DPIV represents 73% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
thymus in thymus DPIV represents 93% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-
vein in vein DPIV represents 80% of the total Gly-L-Pro-4-nitroanilide-hydrolyzing activity Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly-L-Pro-4-nitroanilide + H2O
-
 Mus musculus Gly-L-Pro + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
CD26
-
 Mus musculus
dipeptidyl aminopeptidase IV
-
 Mus musculus
DPIV
-
 Mus musculus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00041
-
-
 Mus musculus Lys[Z(NO2)]-thiazolidide
0.0013
-
-
 Mus musculus Lys[Z(NO2)]-pyrrolidide