Application | Comment | Organism |
---|---|---|
pharmacology | the enzyme is a key target in treatment of acute systemic hypotension | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-adamantyl-3-(5-[2-(2-ethylethoxy)ethoxy]pentyl)urea | i.e. compound 950 | Mus musculus | |
12-(3-adamantan-1-yl-ureido)-dodecanoic acid butyl ester | i.e. AUDA-BE, physiologic consequences of enzyme inhibition in vivo | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | enzyme inhibition decreases plasma levels of proinflammatory cytokines and nitric oxide metabolites while promoting the formation of lipoxins, thus supporting inflammatory resolution | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
male C75BL/6 mice | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Mus musculus | - |
plasma | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme inhibition decreases plasma levels of proinflammatory cytokines and nitric oxide metabolites while promoting the formation of lipoxins, thus supporting inflammatory resolution | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SEH | - |
Mus musculus |