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Literature summary for 3.2.2.22 extracted from
- Essential lysine residues within transmembrane helix 1 of diphtheria toxin facilitate COPI binding and catalytic domain entry (2010), Mol. Microbiol., 76, 1010-1019.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Corynebacterium diphtheriae |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| K213A | the mutation results in a loss of 1-2 logs of cytotoxic potency relative to the wild type fusion protein toxin | Corynebacterium diphtheriae |
| K215A | the mutant retains full cytotoxic activity | Corynebacterium diphtheriae |
| K217A | the mutation results in a loss of 1-2 logs of cytotoxic potency relative to the wild type fusion protein toxin | Corynebacterium diphtheriae |
| K222A | the mutation results in a loss of 1-2 logs of cytotoxic potency relative to the wild type fusion protein toxin | Corynebacterium diphtheriae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Corynebacterium diphtheriae | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Corynebacterium diphtheriae |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| diphtheria toxin | - |
Corynebacterium diphtheriae |
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Release 2023.1 (January 2023)
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