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Literature summary for 3.2.1.176 extracted from
- Effect of pH and temperature on the global compactness, structure, and activity of cellobiohydrolase Cel7A from Trichoderma harzianum (2012), Eur. Biophys. J., 41, 89-98.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Trichoderma harzianum | Q9P8P3 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Avicel PH-101 + H2O | - |
Trichoderma harzianum | ? | - |
? |  |
| crystalline cellulose + H2O | - |
Trichoderma harzianum | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Cel7A | - |
Trichoderma harzianum |
| cellobiohydrolase | - |
Trichoderma harzianum |
| ThCel7A | - |
Trichoderma harzianum |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
recombinant enzyme | Trichoderma harzianum |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 20 | 70 | recombinant enzyme, activity range, profile overview | Trichoderma harzianum |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| additional information | - |
cellobiose-binding influences the enzyme's thermal stability | Trichoderma harzianum |
| 55 | 70 | thermal unfolding behavior of Th Cel7A is found to be a two-step process at pH 5.0. The first step leads to the formation of molten globule-like states between 55°C and 65°C, followed by a second step that was due to the unfolding of the molten globule-like state at temperatures above 70°C | Trichoderma harzianum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | - |
recombinant enzyme | Trichoderma harzianum |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 3 | 6 | recombinant enzyme, activity range, 76% of maximal activity at pH 3..0, inactive at pH 7.0, profile overview | Trichoderma harzianum |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the cellobiohydrolase Cel7A is the major component of total extract produced by Trichoderma and is the key enzyme for efficient degradation of crystalline cellulose | Trichoderma harzianum |
| additional information | tertiary structure analysis at different pH values, small-angle X-ray scattering, overview | Trichoderma harzianum |
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