Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.1.143 extracted from

  • Tulin, A.; Naumova, N.M.; Menon, A.K.; Spradling, A.C.
    Drosophila poly(ADP-ribose) glycohydrolase mediates chromatin structure and SIR2-dependent silencing (2006), Genetics, 172, 363-371.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.143

Cloned(Commentary)

Cloned (Comment) Organism
fusion to enhanced green fluorescent protein and expression in Drosophila melanogaster Drosophila melanogaster

Protein Variants

Protein Variants Comment Organism
additional information decrease or loss of enzyme expression by partial gene deletion or RNA results in mislocalization and hypermodification of silencing protein SIR2 Drosophila melanogaster

Localization

Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila melanogaster poly(ADP-ribose) polymerase and poly(ADP-ribose) glycohydrolase promote chromatin silencing at least in part by regulating the localization and function of silencing protein SIR2 and possible other nuclear proteins ?
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information poly(ADP-ribose) polymerase and poly(ADP-ribose) glycohydrolase promote chromatin silencing at least in part by regulating the localization and function of silencing protein SIR2 and possible other nuclear proteins Drosophila melanogaster ?
-
 ?