Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | 10 mM, stimulates by 70% | Sus scrofa | |
dithiothreitol | 10 mM, stimulates by 70% | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-Naphthylamine | 1 mM, 45% inhibition | Sus scrofa | |
2-naphthalene sulfonic acid | 5 mM, 26% inhibition | Sus scrofa | |
2-Naphthylamine | 1 mM, 50% inhibition | Sus scrofa | |
4-amino-3-hydroxynaphthalene 1-sulfonic acid | 5 m, 79% inhibition | Sus scrofa | |
8-bromoadenosine 3',5'-monophosphate | 5 mM, 13% inhibition | Sus scrofa | |
8-methylaminoadenosine 3',5'-monophosphate | 5 mM, 14% inhibition | Sus scrofa | |
adenine(5'-9)ribofuranoside | 5 mM, 24% inhibition | Sus scrofa | |
adenosine 5'-carboxylic acid | 5 mM, 26% inhibition | Sus scrofa | |
ADP-ribose | - |
Sus scrofa | |
CaCl2 | 5 mM 86% inhibition | Sus scrofa | |
cAMP | - |
Sus scrofa | |
cyclic dAMP | 5 mM, 34% inhibition | Sus scrofa | |
DNA | single-stranded DNA, no inhibition by double-stranded DNA | Sus scrofa | |
histone | histone H1, H2A, H2B and H3 | Sus scrofa | |
MgCl2 | 10 mM, 18% inhibition | Sus scrofa | |
N1-naphthylethanenediamine | 5 mM, 70% inhibition | Sus scrofa | |
NaCl | 400 mM, 75% inhibition | Sus scrofa | |
naphthylamine | - |
Sus scrofa | |
Poly(A) | - |
Sus scrofa | |
poly(I) | - |
Sus scrofa | |
poly(L-Arg) | - |
Sus scrofa | |
poly(L-Lys) | - |
Sus scrofa | |
poly(L-Orn) | - |
Sus scrofa | |
polyvinylsulfate | - |
Sus scrofa | |
protamine | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0018 | - |
Poly(ADP-ribose) | as monomer units | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
59000 | - |
gel filtration | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thymus | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
13.8 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
poly(ADP-ribose)n + H2O | - |
Sus scrofa | ADP-ribose | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 9 | the enzyme is active between pH 6 and 9 | Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1 | - |
2-Naphthylamine | - |
Sus scrofa |