Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | 0.93 mM, stimulates | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoic acid | - |
Rattus norvegicus | |
3',5'-cAMP | - |
Rattus norvegicus | |
arsenite | 1 mM | Rattus norvegicus | |
isopentenyl diphosphate | competitive | Rattus norvegicus | |
additional information | no inhibition by 1 mM p-mercuribenzoate | Rattus norvegicus | |
Plasma albumin | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.7 | 1.2 | (2E,6E)-farnesyl diphosphate | pH 8.8, 37°C | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | slight stimulation | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2E,6E)-farnesyl diphosphate + H2O | Rattus norvegicus | biosynthesis of acyclic sesquiterpenoids | (2E,6E)-farnesol + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2E,6E)-farnesyl diphosphate + H2O | biosynthesis of acyclic sesquiterpenoids | Rattus norvegicus | (2E,6E)-farnesol + diphosphate | - |
? | |
(2E,6E)-farnesyl diphosphate + H2O | diphosphate is the major product, traces of phosphate. The amount of release of diphosphate is approximately equal to the amount of release of farnesol | Rattus norvegicus | (2E,6E)-farnesol + diphosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.8 | - |
- |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
8.5 | 9.1 | pH 8.5: about 40% of maximal activity, pH 9.1: about 65% of maximal activity | Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
5.2 | - |
isopentenyl diphosphate | pH 8.8, 37°C | Rattus norvegicus |