Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ATP | 0.93 mM stimulates rate of hydrolysis | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-butanol | - |
Rattus norvegicus | |
3',5'-cAMP | - |
Rattus norvegicus | |
arsenite | - |
Rattus norvegicus | |
Co2+ | - |
Rattus norvegicus | |
Cu2+ | - |
Rattus norvegicus | |
dimethylallyl diphosphate | - |
Rattus norvegicus | |
farnesoic acid | - |
Rattus norvegicus | |
isopentenyl diphosphate | - |
Rattus norvegicus | |
Mg2+ | loss of about 88% of activity at 10 mM | Rattus norvegicus | |
Mn2+ | - |
Rattus norvegicus | |
additional information | - |
Rattus norvegicus | |
NaF | - |
Rattus norvegicus | |
Plasma albumin | - |
Rattus norvegicus | |
Zn2+ | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.7 | 1.2 | farnesol-diphosphate | - |
Rattus norvegicus | |
4 | 10 | dimethylallyl diphosphate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | 3 mM stimulates the testicular enzyme 4-10fold | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
prenyl diphosphate + H2O | Rattus norvegicus | - |
prenol + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
125fold, partially purified | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
frozen preperations retained activity for 1 month | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
farnesyl diphosphate + H2O | - |
Rattus norvegicus | farnesol + diphosphate | - |
? | |
glucose-6-phosphate + H2O | - |
Rattus norvegicus | glucose + phosphate | - |
? | |
isopentenyl diphosphate + H2O | - |
Rattus norvegicus | isopentenol + diphosphate | - |
? | |
mevalonate-5-phosphate + H2O | - |
Rattus norvegicus | mevalonate + phosphate | - |
? | |
additional information | - |
Rattus norvegicus | ? | - |
? | |
prenyl diphosphate + H2O | - |
Rattus norvegicus | prenol + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
prenol pyrophosphate pyrophosphohydrolase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
enzyme in crude acetone powder | Rattus norvegicus |
8.8 | - |
purified enzyme | Rattus norvegicus |