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Literature summary for 3.1.4.54 extracted from
- Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain (2016), Biochim. Biophys. Acta, 1861, 491-500 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q8BH82 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NAPE-PLD | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | in brain of NAPE-PLD knockout mice, levels of all 6 N-acyl ethanolamines measured are significantly reduced. 2-Arachidonyl glycerol levels are significantly increased in the brainstem of knockout mice, and levels of arachidonic acid are significantly decreased exclusively in brainstem. N-arachidonoyl glycine levels are significantly increased in 4 brain regions and levels of prostaglandin PGE2 are increased in 6 of 8 brain regions in knockout mice | Mus musculus |
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Release 2023.1 (January 2023)
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