Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-bromo-N-[(E)-(2-methyl-1H-indol-3-yl)methyleneamino]benzenesulfonamide | uncompetitive inhibitor | Loxosceles laeta | |
4-methyl-3-oxo-2-(3-pyridylmethylene)benzo[3,4-b]furan-6-yl 4-chloro-benzenesulfonate | mixed-type inhibitor | Loxosceles laeta | |
6-amino-2-((4-cyanobenzyl)thio)pyrimidin-4-yl 4-methylbenzenesulfonate | uncompetitive inhibitor | Loxosceles laeta |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | Loxosceles laeta | - |
ceramide phosphate + choline | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Loxosceles laeta | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Loxosceles laeta | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | - |
Loxosceles laeta | ceramide phosphate + choline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SMase D | - |
Loxosceles laeta |
sphingomyelin phosphodiesterase D | - |
Loxosceles laeta |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00049 | - |
4-bromo-N-[(E)-(2-methyl-1H-indol-3-yl)methyleneamino]benzenesulfonamide | at 37°C, pH not specified in the publication | Loxosceles laeta | |
0.00054 | - |
6-amino-2-((4-cyanobenzyl)thio)pyrimidin-4-yl 4-methylbenzenesulfonate | at 37°C, pH not specified in the publication | Loxosceles laeta | |
0.00059 | - |
4-methyl-3-oxo-2-(3-pyridylmethylene)benzo[3,4-b]furan-6-yl 4-chloro-benzenesulfonate | at 37°C, pH not specified in the publication | Loxosceles laeta |