Any feedback?
Literature summary for 3.1.4.41 extracted from
- A new anti-loxoscelic serum produced against recombinant sphingomyelinase D: results of preclinical trials (2008), Am. J. Trop. Med. Hyg., 79, 463-470.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | recombinant SMase D can replace venom for anti-venom production and therapy | Loxosceles intermedia |
| medicine | recombinant SMase D can replace venom for anti-venom production and therapy | Loxosceles gaucho |
| medicine | recombinant SMase D can replace venom for anti-venom production and therapy | Loxosceles laeta |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Loxosceles intermedia |
- |
Loxosceles laeta |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 64000 | 70000 | SDS-PAGE | Loxosceles intermedia |
| 64000 | 70000 | SDS-PAGE | Loxosceles gaucho |
| 64000 | 70000 | SDS-PAGE | Loxosceles laeta |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Loxosceles gaucho | - |
- |
- |
| Loxosceles intermedia | P0CE81 | SMase D 1 | - |
| Loxosceles intermedia | P0CE83 | SMase D 2 | - |
| Loxosceles laeta | Q8I914 | SMase D 2 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| venom | - |
Loxosceles intermedia | - |
| venom | - |
Loxosceles gaucho | - |
| venom | - |
Loxosceles laeta | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sphingomyelin + H2O | - |
Loxosceles intermedia | ceramide phosphate + choline | - |
? |  |
| sphingomyelin + H2O | - |
Loxosceles gaucho | ceramide phosphate + choline | - |
? | |
| sphingomyelin + H2O | - |
Loxosceles laeta | ceramide phosphate + choline | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | 2 * 32000-35000, SDS-PAGE | Loxosceles intermedia |
| homodimer | 2 * 32000-35000, SDS-PAGE | Loxosceles gaucho |
| homodimer | 2 * 32000-35000, SDS-PAGE | Loxosceles laeta |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Smase D 1 | - |
Loxosceles intermedia |
| Smase D 1 | - |
Loxosceles gaucho |
| Smase D 2 | - |
Loxosceles intermedia |
| Smase D 2 | - |
Loxosceles laeta |
| sphingomyelinase D 1 | - |
Loxosceles intermedia |
| sphingomyelinase D 1 | - |
Loxosceles gaucho |
| sphingomyelinase D 2 | - |
Loxosceles intermedia |
| sphingomyelinase D 2 | - |
Loxosceles laeta |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
