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Literature summary for 3.1.4.4 extracted from
- Clickable substrate mimics enable imaging of phospholipase D activity (2017), ACS Cent. Sci., 3, 1070-1077 .
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | chemical method for imaging phosphatidic acid synthesis by PLD enzymes in live cells. The method is specific to PLD-generated phosphatidic acid. PLD enzymes can accept azidoalcohols as reporters in a transphosphatidylation reaction. The resultant azidolipids are then fluorescently tagged enabling visualization of cellular membranes bearing active PLD enzymes. The method reveals a heterogeneity in PLD activities at both the cellular and subcellular levels | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PLD1 | - |
Homo sapiens |
| PLD2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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