Application | Comment | Organism |
---|---|---|
medicine | promotes tumor cell motility, experimental metastasis, and angiogenesis | Streptomyces chromofuscus |
Cloned (Comment) | Organism |
---|---|
expression in Bac-to-Bac baculovirus in Sf9 insect cells | Streptomyces chromofuscus |
Protein Variants | Comment | Organism |
---|---|---|
T210A | inactive mutant | Streptomyces chromofuscus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-myristoyl-lysophosphatidic acid | - |
Streptomyces chromofuscus | |
1-oleoyl-lysophosphatidic acid | - |
Streptomyces chromofuscus | |
1-palmitoyl-lysophosphatidic acid | - |
Streptomyces chromofuscus | |
bis(para-nitrophenyl)phosphate | inhibition above a concentration of 1 mM | Streptomyces chromofuscus | |
lysophosphatidic acid | 0.001 mM, complexed to albumin, competitive and noncompetitive components | Streptomyces chromofuscus | |
additional information | not affected by dioleoylphosphatidic acid, 1-oleoyl-glycerol, sphingosine, glycerol 3-phosphate | Streptomyces chromofuscus | |
sphingosine-1-phosphate | 0.001 mM, complexed to albumin | Streptomyces chromofuscus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.15 | - |
lysophosphatidylcholine | - |
Streptomyces chromofuscus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasmic vesicle | - |
Streptomyces chromofuscus | 31410 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
125000 | - |
SDS-PAGE | Streptomyces chromofuscus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces chromofuscus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrophenyl thymidine 5'-phosphate + H2O | - |
Streptomyces chromofuscus | 4-nitrophenol + thymidine 5'-phosphate | - |
? | |
bis(para-nitrophenyl)phosphate + H2O | - |
Streptomyces chromofuscus | ? | - |
? | |
CPF4 + H2O | bis-pNPP-derived probe, in which both phenyl moieties are linked to coumarin and fluorescein, respectively | Streptomyces chromofuscus | ? | - |
? | |
lysophosphatidylcholine + H2O | - |
Streptomyces chromofuscus | lysophosphatidic acid + choline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ATX | - |
Streptomyces chromofuscus |
autotaxin | - |
Streptomyces chromofuscus |
NPP2 | - |
Streptomyces chromofuscus |
PLD | - |
Streptomyces chromofuscus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00011 | - |
lysophosphatidic acid | - |
Streptomyces chromofuscus |