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Literature summary for 3.1.4.2 extracted from

  • Mitra, J.; Chowdhury, M
    Purification and characterization of rat uterine glycerylphosphorylcholine diesterase and its tissue-specific induction by 17-beta-estradiol (1991), Endocrinology, 129, 1147-1154.
    View publication on PubMed
Search for more literature for 3.1.4.2

Activating Compound

Activating Compound Comment Organism Structure
17beta-estradiol only in uterine responsive for estradiol Rattus sp.

Inhibitors

Inhibitors Comment Organism Structure
nafoxidine complete inhibition Rattus sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular during proestrous Rattus sp.
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 SDS-PAGE and native PAGE analysis Rattus sp.
105000
-
 gel filtration Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O Rattus sp. cellular phosphatidylcholine catabolic pathway ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification N-acetylglucosamine, N-acetylgalactosamine Rattus sp.

Purification (Commentary)

Purification (Comment) Organism
37-fold purification Rattus sp.

Source Tissue

Source Tissue Comment Organism Textmining
brain low activity Rattus sp.
-
epithelium
-
 Rattus sp.
-
heart low activity Rattus sp.
-
intestine considerable activity Rattus sp.
-
kidney considerable activity Rattus sp.
-
liver low activity Rattus sp.
-
ovary highest activity Rattus sp.
-
skeletal muscle low activity Rattus sp.
-
uterus
-
 Rattus sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.1
-
 proestrous fluid purification Rattus sp.
0.763
-
 in vitro synthesis and purification of the enzyme Rattus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sn-glycero 3-phosphorylcholine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + choline
-
 ?
sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Rattus sp. ?
-
 ?