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Literature summary for 3.1.4.2 extracted from

  • Anfuso, C.D.; Sipione, S.; Lupo, G.; Ragusa, N.; Alberghina, M.
    Characterization of glycerophosphocholine phosphodiesterase activity and phosphatidylcholine biosynthesis in cultured retinal microcapillary pericytes. Effect of adenosine and endothelin-1 (2003), Lipids, 38, 45-52.
    View publication on PubMed
Search for more literature for 3.1.4.2

Activating Compound

Activating Compound Comment Organism Structure
Ca2+
-
 Bos taurus
Cu2+
-
 Bos taurus
Mg2+
-
 Bos taurus
Zn2+
-
 Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
EDTA at 1 mM, about 85% inhibition Bos taurus
N-ethylmaleimide at 3 mM, about 30% inhibition Bos taurus
p-chloromercuribenzoate at 0.1 mM, about 25% inhibition Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.31
-
 sn-glycero 3-phosphorylcholine pH 8.0, 37°C Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome minority of enzymic activity Bos taurus
-
-
plasma membrane majority of enzymic activity Bos taurus 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Bos taurus physiological role of enzyme ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain medium enzymic activity Bos taurus
-
kidney renal epithelial cell culture, low enzymic activity Bos taurus
-
liver medium enzymic activity Bos taurus
-
retina cultured retinal microcapillary pericytes, high enzymic activity Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information physiological role of enzyme Bos taurus ?
-
 ?
sn-glycero 3-phosphorylcholine + H2O
-
 Bos taurus sn-glycerol 3-phosphate + choline
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
-
 Bos taurus