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Literature summary for 3.1.3.51 extracted from
- Dolichyl phosphate phosphatase in rat liver microsomes. Avoidance of the use of detergent in testing the effect of phospholipids on dolichyl phosphate phosphatase (1984), Biochim. Biophys. Acta, 794, 41-48.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| ADP | activates | Rattus norvegicus |  |
| AMP | activates | Rattus norvegicus | |
| ATP | activates | Rattus norvegicus | |
| EDTA | activates | Rattus norvegicus | |
| glucose 1-phosphate | activates | Rattus norvegicus | |
| glucose 6-phosphate | activates | Rattus norvegicus | |
| phosphatidylcholine | activates | Rattus norvegicus | |
| phosphatidylethanolamine | activates | Rattus norvegicus | |
| sphingomyelin | activates | Rattus norvegicus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| NaF | slight inhibition | Rattus norvegicus | |
| phosphate | - |
Rattus norvegicus | |
| phosphatidic acid | 0.00006 mg, 50% inhibition | Rattus norvegicus | |
| phosphatidylinositol | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
| plasma membrane | - |
Rattus norvegicus | 5886 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 300000 | - |
gel filtration, sucrose density gradient centrifugation | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, 24 h, 35% loss of activity | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dolichyl phosphate + H2O | - |
Rattus norvegicus | dolichol + phosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
dolichyl phosphate solution | Rattus norvegicus |
| 37 | - |
dolichyl phosphate particles | Rattus norvegicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00006 | - |
phosphatidic acid | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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