Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme activity is increased at low osmolarity | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme activity is inhibited at high osmolarity | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | RNase III specifically processes the proU mRNA within a conserved secondary structure extending from position +203 to +293 of the transcript | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | RNase III specifically processes the proU mRNA within a conserved secondary structure extending from position +203 to +293 of the transcript | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RNase III | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | blocking of RNase III processing by mutation of the processing site eliminates post-transcriptional osmoregulation of proU | Escherichia coli |
physiological function | the enzyme RNase III initiates rapid degradation of proU mRNA upon hypoosmotic stress, osmoregulation occurs at a post-transcriptional level. Upon osmotic downshift, the enzyme immediately processes the proU mRNA which reduces its half-life from 65 sec to less than 4 sec | Escherichia coli |