Cloned (Comment) | Organism |
---|---|
isolated 125-residue RNase H domain consisiting of residues G436-L560 of polypepitde p6 | Human immunodeficiency virus 1 |
Protein Variants | Comment | Organism |
---|---|---|
E478Q | mutation in isolated RNase H domain, mutant fails to bind RNA/DNA hybrids. Structure of mutant is similar to wild-type | Human immunodeficiency virus 1 |
H539F | mutation in isolated RNase H domain, mutant fails to bind RNA/DNA hybrids. Structure of mutant is similar to wild-type | Human immunodeficiency virus 1 |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
poly(rA)/oligo(dT) | apparent binding constant 3500 per mM | Human immunodeficiency virus 1 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human immunodeficiency virus 1 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
poly(rA)/oligo(dT) + H2O | synthetic hybrid | Human immunodeficiency virus 1 | ? | - |
? |