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Literature summary for 3.1.22.1 extracted from
- DNase II-dependent DNA digestion is required for DNA sensing by TLR9 (2015), Nat. Commun., 6, 5853 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endolysosome | - |
Mus musculus | 36019 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P56542 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNase II | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | key role of DNase II in DNA sensing by the DNA sensor Toll-like receptor 9 (TLR9). DNase II is required for TLR9 activation by bacterial genomic DNA. TLR9 responds to DNA fragments generated by DNase II | Mus musculus |
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