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Literature summary for 3.1.21.10 extracted from
- Human Holliday junction resolvase GEN1 uses a chromodomain for efficient DNA recognition and cleavage (2015), eLife, 4, e12256 .
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystal structure of human HJ resolvase GEN1 complexed with DNA at 3.0 A resolution | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q17RS7 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DNA + H2O | GEN1 contains a chromodomain as an additional DNA interaction site. The GEN1 chromodomain directly contacts DNA and its truncation severely hampers GEN1's catalytic activity | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GEN1 | - |
Homo sapiens |
| Holliday junction resolvase GEN1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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