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Literature summary for 3.1.21.10 extracted from

  • Pereira, A.R.; Reed, P.; Veiga, H.; Pinho, M.G.
    The Holliday junction resolvase RecU is required for chromosome segregation and DNA damage repair in Staphylococcus aureus (2013), BMC Microbiol., 13, 18.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.21.10

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
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-
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Staphylococcus aureus NCTC8325-4
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-
-

Synonyms

Synonyms Comment Organism
crossover junction endodeoxyribonuclease
-
 Staphylococcus aureus
HJ resolvase
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 Staphylococcus aureus
Holliday junction resolvase
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 Staphylococcus aureus
RecU
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 Staphylococcus aureus

General Information

General Information Comment Organism
malfunction enzyme depletion results in the appearance of cells with compact nucleoids, septa formed over the DNA and anucleate cells. Enzyme-depleted cells also show increased septal recruitment of the DNA translocase SpoIIIE, presumably to resolve chromosome segregation defects. Additionally cells are more sensitive to DNA damaging agents such as mitomycin C or UV radiation Staphylococcus aureus
physiological function the enzyme is required for chromosome segregation and DNA damage repair Staphylococcus aureus