Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.21.10 extracted from

  • Sigala, B.; Tsaneva, I.R.
    Functional dissection of the Schizosaccharomyces pombe Holliday junction resolvase Ydc2: in vivo role in mitochondrial DNA maintenance (2003), Eur. J. Biochem., 270, 2837-2847.
    View publication on PubMed
Search for more literature for 3.1.21.10

Protein Variants

Protein Variants Comment Organism
DELTA1-35 mutant enzyme is not able to resolve the synthetic four-way junction X12 Schizosaccharomyces pombe
DELTA1-35/CDELTA15 mutant enzyme is not able to resolve the synthetic four-way junction X12 Schizosaccharomyces pombe
additional information cells that lack Holliday junction resolvase Ydc2 show a significant depletion of mtDNA content. Truncated mutants lacking the SAP motif alone or the whole triple-helix domain are not functional in yeast mitochondria Schizosaccharomyces pombe

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondria wild type enzyme and truncated enzyme forms DELTA1-35 and DELTA1-35/CDELTA15 Schizosaccharomyces pombe
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA + H2O Schizosaccharomyces pombe the enzyme is required for mtDNA transmission and affects mtDNA content ?
-
 ?

Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA + H2O resolves the synthetic four-way junction X12 Schizosaccharomyces pombe ?
-
 ?
DNA + H2O the enzyme is required for mtDNA transmission and affects mtDNA content Schizosaccharomyces pombe ?
-
 ?

Synonyms

Synonyms Comment Organism
Holliday junction resolvase Ydc2
-
 Schizosaccharomyces pombe