Literature summary for 3.1.21.10 extracted from

Giraud-Panis, M.J.E.; P�hler, J.R.G.; Lilley, D.M.J.
T4 endonuclease VII - a zinc containing four-way DNA junction resolving enzyme (1997), Biochem. Soc. Trans., 25, 110.

No PubMed abstract available

Search for more literature for 3.1.21.10

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zn2+	one atom per monomer	Tequatrovirus T4

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
DNA + H2O	Tequatrovirus T4	holliday structure	hydrolyzed DNA	-	?

Organism

Organism	UniProt	Comment	Textmining
Tequatrovirus T4	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
DNA + H2O	DNA topology rather than a sequence determine the cleavage site	Tequatrovirus T4	hydrolyzed DNA	-	?
DNA + H2O	performs 2 separate strand cleavages on the junction, cleaves a number of other structures that have in common bent helices	Tequatrovirus T4	hydrolyzed DNA	-	?
DNA + H2O	holliday structure	Tequatrovirus T4	hydrolyzed DNA	-	?

Subunits

Subunits	Comment	Organism
dimer	-	Tequatrovirus T4

Synonyms

Synonyms	Comment	Organism
endonuclease VII	-	Tequatrovirus T4

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Release 2023.1 (January 2023)