Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q6NQJ6 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Ribonuclease R | - |
Arabidopsis thaliana |
RNR1 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
physiological function | mutants lacking both ribonuclease RNR1 and polynucleotide phosphorylase exhibit embryo lethality. Combination of a RNR1 null mutation with weak polynucleotide phosphorylase mutant alleles leads to chlorotic plants which display a global reduction in RNA abundance. The enzymes catalyze a two-step maturation of mRNA 3' ends, with RNR1 polishing 3' termini created by polynucleotide phosphorylase. The bulky quaternary structure of polynucleotide phosphorylase compared with RNR1 may explain this activity split between the two enzymes. The RNR1 single mutant overaccumulates most mRNA species when compared with the wild type. The excess mRNAs in RNR1 are often present in non-polysomal fractions, and mostly show a substantial increase in stability | Arabidopsis thaliana |