Literature summary for 3.1.11.1 extracted from

Tang, X.; Shen, Y.; Matsui, E.; Matsui, I.
Domain topology of the DNA polymerase D complex from a hyperthermophilic archaeon Pyrococcus horikoshii (2004), Biochemistry, 43, 11818-11827 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of proteins from large subunit DP2(1-100), large subunit DP2(792-1163), and small subunit DP1(1-200)	Pyrococcus horikoshii

Organism

Organism	UniProt	Comment	Textmining
Pyrococcus horikoshii	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Pyrococcus horikoshii

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the yeast two-hybrid system is employed to define regions of intermolecular interaction between small subunit DP1, large subunit DP2, and proliferating cell nuclear antigen PCNA. Intra- and intermolecular interactions between these domains are verified by using surface plasmon resonance	Pyrococcus horikoshii	?	-	?

Subunits

Subunits	Comment	Organism
heterotetramer	heterotetramer L2S2 with two large subunits (DP2) and two small subunits (DP1)	Pyrococcus horikoshii

Synonyms

Synonyms	Comment	Organism
DNA polymerase D	-	Pyrococcus horikoshii
polD	-	Pyrococcus horikoshii

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Release 2023.1 (January 2023)